The Nanomechanics Laboratory investigates mechanical properties of engineered and biological materials at the nano to macro-scale using experimental, analytical, and computational techniques.

The lab’s current research projects include studies of nanostructured materials as well as exploring connections between biological cell mechanics and human disease states.

Recent News

Thu, 02/10/2022

In this Cover Article, the authors report a low-cost microfluidic size exclusion chromatography (μSEC) platform integrated with an on-chip nanoliter sample plug injector for direct EV isolation from human plasma. Its portable and modular design allows flexible coupling with downstream detection modules for clinical diagnostics and real-time EV process monitoring.

Wed, 06/16/2021

In this Cover Article, the authors show that organoids & organ-on-a-chip are synergistic engineering approaches linking with vascularization & innervation to faithfully reconstitute in vitro organ-level structures & functions with high structural fidelity, cellular consistency, environmental control ability, integration as well as throughput.

Mon, 03/22/2021

An international team of scientists has developed an artificial intelligence (AI) platform to assess vascular diseases, which are characterised by the abnormal condition of blood vessels.

Wed, 02/03/2021

Thanks to a painstaking feat of microscopic engineering, the team has now managed to record the biomechanical behavior of mature, individual cell-to-cell junctions.

Thu, 11/12/2020

Regular layer-by-layer 3D printing is old news compared to a new additive manufacturing technique developed by an international team of engineers.

Recent Publications

E. Zhang M. Dao*, G.E. Karniadakis*, S. Suresh*, Science Advances, 8 (2022) eabk0644.

S.Y. Leong, H.B. Ong, H.M. Tay, F. Kong, M. Upadya, L. Gong, M. Dao, R. Dalan, H.W. Hou*, Small, 18 (2022) 2104470. (Cover Article Volume 18, Issue 6; Februrary 10, 2022)

F. Zheng*, Y. Xiao, H. Liu, Y. Fan*, M. Dao*, Advanced Biology, 5 (2021) 2000024. (Cover Article June 2021)

M. Dao, I. MacDonald, R.J. Asaro, Biomechanics and Modeling in Mechanobiology, 20 (2021) 2227-2245. (See SI Movie 1 & SI Movie 2)